Browsing Theses by Subject "p53, BRAF, P53 target genes, melanoma, and UV light"

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Differential Activation of P53 Downstream Genes in Malignant Melanoma Cells with Different Genetic Contexts

Sun, Huiyun (2017-09-11)

This work aims to understand the differential activation of P53 and its downstream genes in response to UV irradiation in different genetic contexts of braf and p53. Human melanoma SK-MEL-28 (mutant BRAF and mutant P53), ...