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Lysolecithin induction of cell fusion.

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dc.contributor.author Cota, Gene F.
dc.date.accessioned 2012-08-06T15:42:22Z
dc.date.available 2012-08-06T15:42:22Z
dc.date.created 1985 en_US
dc.date.issued 2012-08-06
dc.identifier.uri http://hdl.handle.net/123456789/2000
dc.description v, 45 leaves en_US
dc.description.abstract The phospholipid lysolecithin was tested in various concentrations, temperatures and environments for its effects on cell fusion, disintegration and mortality. Cholesterol and mineral oil were both assayed for their actions in reducing cell loss. Temperature extremes both high and low proved to be cytotoxic and cytolytic although higher temperatures increased cell fusion events. Cholesterol was found to be of little significance in decreasing lysolecithin's cytotoxic effects. Mineral oil solutions of lysolecithin did not significantly improve cell survival, but these mineral oil solutions proved to be significant in the fusion of cells without the presence of lysolecithin. A mechanism is proposed for this mineral oil induced cell fusion. en_US
dc.language.iso en_US en_US
dc.subject Cell hybridization. en_US
dc.subject Lysolecithin. en_US
dc.title Lysolecithin induction of cell fusion. en_US
dc.type Thesis en_US
dc.college las en_US
dc.advisor Gaylen J. Neufeld en_US
dc.department biological sciences en_US

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